Trexall

Trexall is a brand name for the medication methotrexate. Methotrexate is an antimetabolite and antifolate drug that is used in the treatment of several conditions. It is primarily prescribed for certain types of cancer, including leukemia, lymphoma, breast cancer, head and neck cancer, and lung cancer. In lower doses, Trexall is also used to manage severe cases of rheumatoid arthritis that have not responded to other treatments. Additionally, it is prescribed for severe, recalcitrant psoriasis that has not been adequately controlled by other therapies.

Trexall works by interfering with the rapid growth of cells. In cancer treatment, it slows or stops the growth of cancer cells. In autoimmune conditions like rheumatoid arthritis and psoriasis, it suppresses the immune system's overactivity, which is responsible for the inflammation and tissue damage associated with these diseases. The drug can be administered orally in tablet form or injected.

Like all medications, Trexall can cause side effects. Common side effects may include nausea, vomiting, diarrhea, mouth sores, fatigue, and hair loss. More serious side effects can occur, including liver damage, kidney damage, lung problems, and bone marrow suppression, which can lead to increased risk of infection and bleeding. Patients taking Trexall require regular monitoring by a healthcare professional to check for these potential issues and to adjust the dosage as needed. It is crucial for patients to discuss their medical history and any other medications they are taking with their doctor before starting Trexall.