Sildenafiili

Sildenafiili is the active ingredient in the medication Viagra and several other prescription drugs. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Sildenafiili is primarily used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis during sexual stimulation, which helps men achieve and maintain an erection.

The mechanism of action involves inhibiting the PDE5 enzyme. This enzyme normally breaks down cyclic guanosine monophosphate (cGMP), a substance that relaxes smooth muscles in the penis and allows blood to flow in. By inhibiting PDE5, sildenafiili increases cGMP levels, leading to enhanced smooth muscle relaxation and improved blood flow, facilitating an erection.

Sildenafiili is taken orally, typically about an hour before sexual activity. It is not an aphrodisiac and requires sexual stimulation to be effective. The effects can last for several hours. Common side effects include headache, flushing, nasal congestion, and visual disturbances such as blurred vision or sensitivity to light.

It is crucial that sildenafiili is only used under the prescription and supervision of a healthcare professional. It is contraindicated in individuals taking nitrate medications, as this combination can cause a dangerous drop in blood pressure. Sildenafiili is also not recommended for individuals with certain heart conditions or other specific medical issues. It is important to discuss any pre-existing medical conditions and other medications with a doctor before starting treatment with sildenafiili.