S8A

S8A is a gene that encodes a protein belonging to the SEC8 gene family. This family of proteins is involved in the exocyst complex, a multi-protein structure essential for vesicle trafficking and exocytosis in eukaryotic cells. The exocyst complex plays a critical role in the targeted delivery of vesicles to specific sites on the plasma membrane, a process crucial for various cellular functions including cell growth, division, and secretion.

The protein produced by the S8A gene is a component of this exocyst complex. While the precise function of each subunit can be complex and context-dependent, S8A's involvement in the exocyst suggests a role in mediating the tethering of vesicles to the target membrane before fusion. This interaction is vital for the proper regulation of exocytosis, ensuring that cellular products are released at the correct locations and times. Mutations or dysregulation of S8A, and other exocyst components, have been implicated in various diseases, including cancer, where uncontrolled cell growth and metastasis are often linked to aberrant vesicle trafficking. Research into S8A and its role within the exocyst complex continues to shed light on fundamental cellular processes and potential therapeutic targets.