RNAketjun

RNAketjun is a protein complex that plays a crucial role in the regulation of gene expression in eukaryotic cells. The name "RNAketjun" is derived from the combination of "RNA" and "ketjun," which is a Finnish word meaning "chain." This complex is responsible for the processing and export of messenger RNA (mRNA) from the nucleus to the cytoplasm, where it can be translated into proteins.

The RNAketjun complex is composed of several proteins, including the RNA-binding protein TBP (TATA-box binding protein), the RNA helicase DHX9, and the RNA export factor Mex67. These proteins work together to unwind the secondary structure of the mRNA, facilitate its transport through the nuclear pore complex, and assist in its export into the cytoplasm.

The RNAketjun complex is essential for proper gene expression, as it ensures that only mature and functional mRNAs are translated into proteins. Dysregulation of the RNAketjun complex has been linked to various diseases, including cancer and neurodegenerative disorders. Therefore, understanding the mechanisms by which the RNAketjun complex functions is of great importance for the development of new therapeutic strategies.