Q41L

Q41L is a variant of the SARS-CoV-2 virus, which causes COVID-19. It was first identified in South Africa in November 2021 and has since been detected in several other countries. The variant is named after the amino acid sequence at the spike protein, which is a key target for vaccines and antibodies. Q41L is of particular concern because it has been found to be resistant to some monoclonal antibodies, which are a type of treatment used to neutralize the virus. This resistance is thought to be due to a single amino acid change in the spike protein, which allows the virus to evade the immune response. The variant has been associated with increased transmissibility and has been detected in several outbreaks, including in healthcare settings and among the unvaccinated. However, it is important to note that the overall impact of Q41L on the global pandemic is still being studied, and its significance may change as more data becomes available.