Parenchymverkleinerung

Parenchymverkleinerung, also known as parenchymous atrophy, refers to the reduction in size or number of parenchyma cells in an organ or tissue. Parenchyma is the primary functional tissue in many organs, such as the liver, lungs, and kidneys, where it performs essential metabolic and secretory functions. Atrophy can occur due to various factors, including chronic disease, malnutrition, or disuse. For example, in the liver, parenchymous atrophy can result from chronic hepatitis or cirrhosis, leading to a decrease in liver function. Similarly, in the lungs, atrophy can occur due to chronic obstructive pulmonary disease (COPD), causing a reduction in lung volume and impaired gas exchange. The process of parenchymous atrophy is typically reversible if the underlying cause is addressed, but in severe cases, it can lead to permanent damage and organ failure.