PSMA4

PSMA4, also known as Prostate Membrane Antigen Like 4, is a protein-coding gene. It encodes a protein that is part of the proteasome, a complex responsible for breaking down unwanted or damaged proteins within cells. The proteasome plays a crucial role in various cellular processes, including cell cycle regulation, apoptosis (programmed cell death), and gene expression. PSMA4 specifically is a subunit of the 20S core particle of the proteasome. Mutations or alterations in PSMA4 expression have been implicated in certain diseases, though its precise role in these conditions is still an area of active research. In the context of cancer, particularly prostate cancer, there has been interest in PSMA4 due to its association with the proteasome, a known therapeutic target. Further research is ongoing to fully elucidate the functions of PSMA4 and its potential involvement in disease pathogenesis and treatment strategies.