P2RiboseNAD
P2RiboseNAD is a protein that plays a crucial role in the metabolism of nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for various cellular processes. NAD+ is involved in energy metabolism, DNA repair, and gene expression regulation. P2RiboseNAD is a member of the P2X family of proteins, which are involved in the regulation of ion channels. Specifically, P2RiboseNAD is a ribosyltransferase that catalyzes the transfer of a ribose group from nicotinamide mononucleotide (NMN) to NAD+, producing nicotinamide mononucleotide adenine dinucleotide (NMNAD+). This reaction is a key step in the salvage pathway of NAD+, which helps maintain cellular NAD+ levels. P2RiboseNAD is expressed in various tissues, including the brain, liver, and kidney, and its activity is regulated by several factors, including NAD+ levels and cellular energy status. Dysregulation of P2RiboseNAD activity has been implicated in various diseases, including neurodegenerative disorders, metabolic syndromes, and cancer. Further research is needed to fully understand the role of P2RiboseNAD in health and disease.