Nup145

Nup145 is a gene that encodes a protein involved in nuclear pore complex assembly in yeast. The nuclear pore complex is a large protein structure that spans the nuclear envelope and regulates the transport of molecules between the nucleus and the cytoplasm. Nup145 is a component of the nuclear pore complex, and its proper function is essential for the integrity and activity of the nucleus. Studies have shown that mutations in the Nup145 gene can lead to defects in nuclear pore formation and function, resulting in various cellular abnormalities. The Nup145 protein is thought to interact with other nuclear pore proteins, playing a role in the structural organization and assembly of the complex. Research into Nup145 has provided valuable insights into the intricate mechanisms governing nuclear transport and the fundamental processes of cell biology. Its role in nuclear pore assembly makes it a target of interest for understanding both normal cellular function and the potential consequences of disrupted nuclear transport in disease states.