Nasetyyliglukosamiinista
Nasetyyliglukosamiini (N-Glycosylation) is a post-translational modification process in which a glycan (sugar molecule) is attached to an asparagine residue in a protein. This process occurs in the endoplasmic reticulum (ER) of eukaryotic cells and is crucial for the proper folding, stability, and function of many proteins. The glycan attached during N-glycosylation typically consists of a core structure of two N-acetylglucosamine (GlcNAc) residues and one mannose (Man) residue, which can be further modified and elongated in the Golgi apparatus.
N-Glycosylation plays a vital role in various biological processes, including protein trafficking, cell signaling, and immune
Abnormalities in N-glycosylation have been linked to several diseases, including lysosomal storage disorders, neurodegenerative diseases, and
In summary, N-glycosylation is a critical post-translational modification process that plays a crucial role in various