MHCpresentations
MHC presentations refers to the process by which peptide antigens are displayed on the surface of cells by major histocompatibility complex (MHC) molecules for recognition by T cells. In humans, MHC genes are called human leukocyte antigen (HLA) genes, and their extensive polymorphism shapes which peptides can be bound and presented to the immune system.
Two main classes operate in distinct pathways. MHC class I molecules present endogenous peptides, derived from
Cross-presentation is a specialized process wherein certain antigen-presenting cells, notably dendritic cells, present extracellular antigens on