LY6D
Ly6D, short for lymphocyte antigen 6 family member D, is a cell-surface protein that belongs to the Ly6/LU domain family. It is a small glycoprotein anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor and is expressed on certain lymphoid-lineage cells.
In mice, Ly6D expression identifies a subset of common lymphoid progenitors (CLPs) that are biased toward B
Structure and family context: Ly6D is one of several proteins in the Ly6/LY6E superfamily, characterized by
Clinical and research relevance: Ly6D is mainly used in hematopoietic research as a marker to distinguish progenitor
See also: Ly6/LU domain protein family; B cell development; common lymphoid progenitors.