LCsprayionisationMS
LC-ESI-MS stands for Liquid Chromatography-Electrospray Ionization-Mass Spectrometry. It is a powerful analytical technique that combines the separation capabilities of liquid chromatography with the sensitive detection of mass spectrometry. In this hyphenated technique, a liquid chromatography system separates the components of a complex mixture based on their physical and chemical properties. As each separated component elutes from the LC column, it is directly introduced into an electrospray ionization source.
Electrospray ionization is a soft ionization method that generates ions from molecules in solution. The liquid
The mass spectrometer analyzes these ions based on their mass-to-charge ratio (m/z). By measuring the m/z of