Kremen2

Kremen2 is a protein that plays a role in cell division and chromosome segregation. It is a component of the mitotic spindle, a structure that forms during cell division to ensure that chromosomes are evenly distributed between daughter cells. Kremen2 is involved in the regulation of kinetochore-microtubule attachments, which are crucial for the proper movement of chromosomes. Its precise functions are still being investigated, but it is thought to contribute to the stability and dynamics of these attachments. Research suggests that Kremen2 may interact with other proteins involved in spindle assembly and chromosome passenger complex functions. Dysregulation of Kremen2 has been implicated in certain chromosomal abnormalities, highlighting its importance in maintaining genomic stability. Studies have explored its expression patterns in various tissues and its potential involvement in cancer development. Further research is ongoing to fully elucidate the complex roles of Kremen2 in cellular processes.