Kreatiinikineasi

Kreatiinikineasi, also known as creatine kinase (CK), is an enzyme found in various tissues, including muscles, brain, and red blood cells. It plays a crucial role in the metabolism of creatine, an amino acid derivative that serves as an energy reserve in muscle cells. The primary function of creatine kinase is to catalyze the reversible transfer of a phosphate group from creatine phosphate to ADP, producing ATP and creatine. This reaction helps maintain the energy supply in muscle cells during intense physical activity.

Creatine kinase exists in multiple isoforms, each with distinct tissue distributions and functions. The most well-known isoforms are CK-MM (muscle-specific), CK-BB (brain-specific), and CK-MB (found in heart muscle and skeletal muscle). Elevated levels of creatine kinase in the blood, particularly CK-MB, are indicative of myocardial infarction (heart attack) and are used as a diagnostic marker.

Creatine kinase activity can be measured in serum or other bodily fluids to assess muscle damage or heart health. However, it is important to note that creatine kinase levels can also be elevated due to other conditions, such as muscle trauma, muscular dystrophies, or certain medications. Therefore, interpretation of creatine kinase levels should be done in conjunction with clinical context and other diagnostic tests.

In summary, creatine kinase is a vital enzyme involved in energy metabolism, particularly in muscle cells. Its activity and isoforms provide valuable information for diagnosing muscle damage and heart conditions.