Karboksüülsünteesil

Karboksüülsünteesil refers to the biochemical process of carboxylation, which is the addition of a carboxyl group (-COOH) to a molecule. This reaction is fundamental in many metabolic pathways across living organisms. Enzymes called carboxylases catalyze these reactions, often requiring a source of carbon dioxide. A common example is the carboxylation of pyruvate to form oxaloacetate, a crucial step in the citric acid cycle. This process also plays a role in the biosynthesis of fatty acids, where acetyl-CoA is carboxylated to malonyl-CoA. In plants, carboxylation is central to photosynthesis, specifically in the Calvin cycle, where carbon dioxide is fixed onto RuBP. The biological significance of karboksüülsünteesil lies in its role in energy production, nutrient assimilation, and the synthesis of essential biomolecules. Deficiencies or dysfunctions in carboxylase enzymes can lead to various metabolic disorders.