Isoformák

Isoforms are different forms of a protein that arise from alternative splicing of a single gene. This process involves the removal of different segments of pre-mRNA, resulting in multiple mRNA transcripts that can encode different proteins. Isoforms can have distinct functions, structures, or cellular localizations, even though they originate from the same gene. The study of isoforms is crucial in understanding the complexity of protein function and regulation in biological systems. They play significant roles in various physiological and pathological processes, including development, disease progression, and drug response. The identification and characterization of isoforms have advanced with the advent of high-throughput sequencing technologies, providing deeper insights into the proteome and its dynamics.