Igf1e1

Igf1e1, also known as Insulin-like growth factor 1 isoform epsilon 1, is a splice variant of the Insulin-like growth factor 1 (IGF-1) gene. IGF-1 is a hormone that plays a crucial role in growth and development, particularly in childhood. The standard IGF-1 protein is known to promote cell growth, proliferation, and survival.

The Igf1e1 isoform arises from alternative splicing of the IGF-1 gene. This alternative splicing results in a protein with a slightly different structure compared to the canonical IGF-1. While the exact functional differences between Igf1e1 and other IGF-1 isoforms are still under investigation, research suggests that Igf1e1 may have distinct biological activities or tissue-specific roles. Studies have indicated its potential involvement in processes such as muscle regeneration and metabolic regulation.

The expression of Igf1e1 can vary depending on physiological conditions and developmental stages. Understanding the specific functions and regulatory mechanisms of Igf1e1 is an ongoing area of research, contributing to a broader understanding of the complex IGF-1 signaling pathway and its impact on health and disease. Further research is needed to fully elucidate its precise physiological roles and potential therapeutic applications.