INO80B

INO80B is a gene that encodes a protein belonging to the INO80 complex, a chromatin remodeling complex. The INO80 complex plays a crucial role in regulating gene expression by altering the structure of chromatin, which is the complex of DNA and proteins that forms chromosomes. This remodeling process can make DNA more or less accessible to transcription machinery, thereby influencing whether genes are turned on or off.

The protein encoded by INO80B is a subunit of this larger complex. While the precise function of each INO80 complex subunit is still under investigation, it is understood that they work in concert to perform essential cellular functions. These functions are not limited to gene transcription but also include DNA repair, DNA replication, and chromosome segregation. Defects in chromatin remodeling complexes, including those involving INO80B, have been linked to various diseases, including cancer and developmental disorders. Research into INO80B and its role in the INO80 complex is ongoing, aiming to further elucidate its specific contributions to cellular processes and its potential implications in disease. Understanding the precise mechanisms of INO80B can offer insights into therapeutic strategies for conditions associated with chromatin dysregulation.