IFNGR12

IFNGR12 refers to Interferon Gamma Receptor 1-like 2. This gene encodes a protein that is part of the interferon gamma receptor complex. The interferon gamma receptor is a transmembrane protein complex that plays a crucial role in the cellular response to interferon gamma (IFN-γ), a key cytokine in the immune system. IFN-γ is involved in regulating immune and inflammatory responses, and its signaling pathway is essential for fighting infections and controlling cell growth. The IFNGR1 protein, along with IFNGR2, forms the heterodimeric receptor that binds IFN-γ. While IFNGR12 is annotated as a related gene, its precise function and contribution to the IFN-γ receptor complex or its signaling pathway are subjects of ongoing research and may differ from the canonical IFNGR1. Understanding the specific role of IFNGR12 is important for a complete picture of IFN-γ mediated immunity and potential therapeutic interventions targeting this pathway.