Hematoksüliineosiinina

Hematoksüliineosiinina is the Estonian term for Hematoxylin and Eosin staining, often abbreviated as H&E. This is the most widely used tissue staining method in medical histology. It is a differential stain, meaning it uses multiple dyes to distinguish between different tissue components. The "hematoxylin" component is a basic dye that stains cell nuclei a deep blue or purple color due to its affinity for acidic nucleic acids within the nucleus. The "eosin" component is an acidic dye that stains cytoplasm and extracellular matrix a pink to reddish color. This contrast allows pathologists and researchers to visually differentiate between various cellular structures, such as nuclei, cytoplasm, and connective tissue, within a tissue sample. H&E staining is crucial for diagnosing diseases, particularly cancer, by enabling the examination of cellular morphology and tissue architecture. The staining process involves several steps, including tissue fixation, embedding, sectioning, and then applying the hematoxylin and eosin dyes. Variations in staining intensity and color can sometimes indicate pathological changes.