Haloalkyl
Haloalkyl refers to an alkyl substituent in which one or more hydrogen atoms have been replaced by halogen atoms such as fluorine, chlorine, bromine, or iodine. The resulting substituent is attached to the rest of the molecule at the carbon bearing the halogen. Common mono-haloalkyl groups include chloromethyl (-CH2Cl) and bromomethyl (-CH2Br). Haloalkyl groups can also be formed at other positions on the chain, giving substituents such as 2-chloroethyl (-CH2-CH2Cl) or 3-chloropropyl (-CH2-CH2-CH2Cl). More heavily halogenated variants, such as dichloro- or difluoroalkyl groups, also occur.
Haloalkyl groups are reactive centers in organic synthesis. The carbon–halogen bond can act as a leaving group
In synthesis, haloalkyl substituents are introduced by halogenation of appropriate precursors or by halomethylation/haloethylation strategies. Safety