FcRL2

FcRL2, also known as Fc receptor-like 2, is a protein encoded by the Fcrl2 gene. It belongs to the Fc receptor-like (FcRL) family, which are transmembrane proteins characterized by structural similarities to Fc receptors but lacking direct ligand-binding activity for immunoglobulin isotypes. FcRL2 is primarily expressed on B cells, with a distinct expression pattern across different B cell subsets. Its precise function is still under investigation, but it is thought to play a role in regulating B cell development, activation, and immune responses. Research suggests that FcRL2 may interact with other cell surface molecules or intracellular signaling pathways to modulate B cell function. Studies have explored its potential involvement in autoimmune diseases and lymphoproliferative disorders. The discovery and characterization of FcRL2 contribute to a broader understanding of the complex regulatory mechanisms governing B cell immunity. Further research is ongoing to elucidate its specific signaling pathways and its contributions to both healthy and pathological immune states.