Diplóteno

Diplóteno, also known as diploë, is a thin layer of connective tissue that separates the inner and outer layers of certain bones. This layer is particularly prominent in the skull, where it is found between the outer compact bone (cortical bone) and the inner spongy bone (cancellous bone). The diploë is rich in blood vessels, nerves, and lymphatic tissue, which makes it a site of active hematopoiesis, the process by which blood cells are produced. This layer is crucial for the growth and development of the skull, as it allows for the expansion of the brain during childhood and adolescence.

In the skull, the diploë is typically about 2-3 millimeters thick and is most abundant in the areas where the skull is most likely to expand, such as the frontal and parietal bones. It is also present in other bones, including the ribs, sternum, and vertebrae, but it is not as prominent as in the skull. The diploë plays a significant role in the body's immune response, as it contains a large number of immune cells that can help protect the body from infection.

The diploë is also a site of active bone remodeling, as it is constantly being broken down and rebuilt by osteoblasts and osteoclasts. This process is essential for maintaining the strength and integrity of the bone. In some cases, the diploë can be affected by disease or injury, leading to conditions such as diploë osteomyelitis, a type of bone infection that can occur in the skull.