Dihidrofolátsavvá

Dihidrofolátsavvá is the Hungarian term for dihydrofolate. It is a crucial intermediate in the metabolism of folate, also known as vitamin B9. Dihydrofolate is formed from folic acid through the action of the enzyme dihydrofolate reductase. This enzyme adds a hydrogen atom to folic acid. Dihydrofolate then undergoes another reduction step, also catalyzed by dihydrofolate reductase, to become tetrahydrofolate (THF). Tetrahydrofolate is the biologically active form of folate and is essential for numerous metabolic processes in the body. These include the synthesis of purines and pyrimidines, the building blocks of DNA and RNA, and the metabolism of amino acids. Therefore, dihydrofolátsavvá plays a vital role in cell growth, division, and repair. Disruptions in dihydrofolate metabolism can have significant health consequences, and drugs that inhibit dihydrofolate reductase are used in various medical treatments, such as chemotherapy for cancer and antimicrobial therapies.