CpGdeler

CpGdeler is a term that refers to CpG dinucleotides located within a specific genomic region that is susceptible to enzymatic cleavage. CpG dinucleotides are sequences of cytosine (C) followed by guanine (G). In mammals, cytosines in CpG dinucleotides are often methylated, a process that plays a role in gene regulation. CpG islands are regions of the genome that are enriched in CpG dinucleotides and are often found in the promoter regions of genes. Enzymes, such as restriction enzymes, can be used to cleave DNA at specific sequences, including those containing CpG sites. The term "CpGdeler" likely describes a DNA fragment or region that is specifically targeted for cleavage at these CpG sites by a particular enzyme or experimental manipulation. Understanding CpGdeler regions can be important in molecular biology research, particularly in studies involving DNA methylation analysis, gene expression studies, or the development of DNA-based diagnostic tools. The precise biological or experimental context in which "CpGdeler" is used would further clarify its specific meaning and application.