Connexine
Connexins are a family of transmembrane proteins that assemble to form gap junctions. Gap junctions are specialized protein channels that directly connect the cytoplasm of adjacent cells, allowing for the passage of small molecules and ions. This intercellular communication is crucial for a wide range of physiological processes, including cell-to-cell signaling, electrical coupling in excitable tissues like the heart and brain, and the coordinated growth and development of tissues.
There are numerous connexin genes identified in mammals, and the specific connexin subtypes expressed in a