CoF2

COF2, or carbonyl difluoride, is a chemical compound with the formula COF2. It consists of a carbonyl group with two fluorine atoms attached to the carbon, giving a linear F–C(=O)–F structure. It is a colorless gas at room temperature and pressure and is highly reactive, particularly with moisture.

COF2 is classified as an acyl fluoride and is readily hydrolyzed by water to carbon dioxide and hydrogen fluoride: COF2 + H2O → CO2 + 2 HF. It can also react with nucleophiles such as amines and alcohols to form amides and esters, respectively, with the concomitant loss of HF. Its reactivity makes it useful in selective fluorination and in the preparation of acyl fluoride functionalities, though its handling requires strict moisture exclusion.

Synthesis methods for COF2 include the fluorination of carbon monoxide with fluorine in specialized industrial settings. Alternative routes involve the fluorination of phosgene with fluoride sources. Because of the hazardous nature of fluorine chemistry and the moisture sensitivity of COF2, production and handling are confined to controlled facilities with appropriate safety measures.

Applications of COF2 are mainly in specialized chemical research and industry. It serves as a source of the carbonyl fluoride group and as a fluorinating reagent for converting substrates to acyl fluoride derivatives. Due to its toxicity and reactivity with water, COF2 is not common in standard laboratory practice and is used under strictly controlled conditions.

Safety and handling: COF2 is toxic and corrosive. It hydrolyzes upon contact with moisture, producing HF. It should be stored and used under dry, inert conditions with proper ventilation and personal protective equipment.