Ca2export

Ca2export is a protein that plays a crucial role in calcium homeostasis within cells. It is a member of the calcium ATPase family, which includes other proteins like the sarcoplasmic reticulum calcium ATPase (SERCA) and the plasma membrane calcium ATPase (PMCA). Ca2export is primarily expressed in the plasma membrane of various cell types, including neurons, muscle cells, and certain types of epithelial cells.

The primary function of Ca2export is to actively transport calcium ions out of the cell, thereby maintaining a low intracellular calcium concentration. This process is essential for various cellular functions, such as muscle contraction, neurotransmitter release, and cell signaling. Ca2export achieves this by using ATP to pump calcium ions against their concentration gradient, from the cytoplasm to the extracellular space.

Ca2export is regulated by several mechanisms, including phosphorylation, which can modulate its activity and expression. This regulation is important for maintaining calcium homeostasis during different physiological states and in response to various stimuli.

Ca2export has been studied extensively in the context of neurological disorders, as abnormal calcium handling is implicated in conditions such as epilepsy and neurodegenerative diseases. Research on Ca2export aims to understand its role in these disorders and to develop potential therapeutic targets.