COPS5

COPS5, also known as Candidate of Subset 5, is a gene that encodes a protein belonging to the COP9 signalosome complex. This complex is a crucial regulator of protein degradation pathways and signal transduction in eukaryotic cells. The COP9 signalosome is a multi-subunit protein complex that plays a role in mediating the activity of the ubiquitin-proteasome system, particularly in the turnover of specific regulatory proteins.

The protein produced by the COPS5 gene interacts with other subunits to form the functional COP9 signalosome. This complex is involved in various cellular processes, including photomorphogenesis in plants, cell cycle progression, and DNA damage repair. Dysregulation of COPS5 has been implicated in certain diseases, suggesting its importance in maintaining cellular homeostasis. Research into COPS5 and its associated complex continues to uncover its diverse roles in fundamental biological mechanisms.