CD38positiva

CD38positive is a term used in the field of immunology to describe a subset of B cells that express the CD38 surface marker. CD38 is a protein that is involved in various cellular processes, including cell growth, differentiation, and apoptosis. The expression of CD38 on B cells is associated with their activation and differentiation into plasma cells, which are responsible for producing antibodies. CD38positive B cells are often found in the germinal centers of lymph nodes, where they undergo somatic hypermutation and class switch recombination to generate diverse and high-affinity antibodies. These cells play a crucial role in the adaptive immune response, particularly in the production of antibodies against pathogens. The study of CD38positive B cells is important for understanding the mechanisms of humoral immunity and for developing strategies to modulate immune responses in diseases such as autoimmune disorders and cancer.