CCR5ttä
CCR5 is a chemokine receptor that plays a crucial role in the immune system, particularly in the response to HIV infection. It is a G-protein-coupled receptor that binds to the chemokine CCL5 (also known as RANTES). CCR5 is expressed on the surface of various immune cells, including T cells, macrophages, and dendritic cells. The binding of CCL5 to CCR5 initiates a signaling cascade that leads to the migration of these cells towards sites of infection or inflammation.
The CCR5 gene is located on chromosome 3 in humans. It consists of five exons and four
CCR5 is a target of HIV, as the virus uses CCR5 as a co-receptor to enter T
Mutations in the CCR5 gene can lead to a reduced or absent expression of the CCR5 protein.
In summary, CCR5 is a chemokine receptor that plays a vital role in the immune response and