C5L2

C5L2 refers to a specific type of protein, a subunit of the nuclear import receptor importin-5. Importin-5 is a protein that plays a crucial role in the transport of molecules into the nucleus of eukaryotic cells. It is part of the larger importin-beta superfamily, which are responsible for mediating the movement of proteins and other macromolecules across the nuclear envelope.

The C5L2 protein specifically interacts with cargo molecules that are targeted for nuclear import. This interaction facilitates the binding of the cargo to importin-5 and subsequent translocation through the nuclear pore complex. The precise function and binding partners of C5L2 are areas of ongoing research, but it is understood to be a key component in regulating nuclear transport pathways. Dysregulation of nuclear import can have significant implications for cellular function and has been implicated in various diseases.