BCL10L2

BCL10L2 is a protein-coding gene located on chromosome 19q13.2. It is a member of the BCL10 family of proteins, which are involved in various cellular processes, including immune response, cell proliferation, and apoptosis. BCL10L2 encodes a protein that functions as a transcriptional coactivator, interacting with other proteins to regulate gene expression. This protein is known to play a role in the regulation of the NF-kappaB pathway, which is crucial for immune response and inflammation. Mutations in the BCL10L2 gene have been associated with certain types of cancer, particularly in the context of chronic lymphocytic leukemia (CLL). However, the exact role of BCL10L2 in cancer development and progression is still an active area of research. The gene is also involved in the regulation of other cellular processes, such as cell cycle regulation and DNA repair. Overall, BCL10L2 is a multifunctional protein with significant implications for both normal cellular function and disease pathogenesis.