Antisialogogues
Antisialogogues are a class of drugs that reduce the flow of saliva. They are also known as anticholinergics or antimuscarinics because they primarily work by blocking the action of acetylcholine, a neurotransmitter that stimulates salivary glands. Saliva production is regulated by the parasympathetic nervous system, and acetylcholine is a key mediator in this process. By inhibiting acetylcholine receptors on the salivary glands, antisialogogues decrease the amount of saliva secreted.
These medications are used to manage conditions characterized by excessive salivation, or sialorrhea. This can include
Common antisialogogues include atropine, scopolamine, glycopyrrolate, and benztropine. While effective, these drugs can have various side