Adjuvantide

Adjuvantide is a term used in the field of immunology to describe a substance that enhances the immune response to an antigen. Adjuvants are often used in vaccines and immunotherapies to improve the body's ability to recognize and respond to pathogens or cancer cells. They work by stimulating immune cells, such as dendritic cells and macrophages, to produce cytokines and other immune mediators that amplify the immune response. Adjuvantide can be classified into two main categories: oil-in-water emulsions, which include substances like Montanide ISA 51 and Montanide ISA 720, and water-in-oil emulsions, such as MF59. These adjuvants are designed to prolong the release of antigens, increase their uptake by immune cells, and enhance the overall effectiveness of the immune response. The choice of adjuvantide depends on the specific application, the type of antigen, and the desired immune response.