Acrystallins
Acrystallins are a family of proteins that, in vertebrates, are primarily found in the lens of the eye. Their name derives from their function as structural components of the lens, contributing to its transparency and refractive properties. While initially thought to be exclusively lens-specific, acrystallins have since been identified in other tissues and even in invertebrates, suggesting broader roles.
The most well-characterized acrystallins are alpha-, beta-, and gamma-crystallins. These proteins are highly soluble and tend
Beyond their structural role, research has uncovered potential functional activities for acrystallins. Some have exhibited chaperone-like