APAF1binding

APAF1binding is a human gene that encodes a protein involved in apoptosis, the process of programmed cell death. The protein produced by this gene, Apoptotic protease activating factor 1, is a key component of the apoptosome, a large protein complex that initiates caspase activation. Caspases are a family of proteases that execute the cellular dismantling process during apoptosis. The APAF1binding gene is located on chromosome 12. Mutations or dysregulation of this gene can have significant implications for cell survival and disease development, particularly in cancer where uncontrolled cell proliferation is a hallmark. Understanding the function of APAF1binding and its role in apoptosis is crucial for developing targeted therapies for various diseases.