ABCB2

ABCB2 is a gene that encodes a protein belonging to the ATP-binding cassette (ABC) transporter superfamily. These proteins are involved in transporting a wide variety of molecules across cellular membranes. The ABCB2 protein specifically is thought to function as a membrane transporter, though its precise substrates and physiological roles are still under investigation. It is expressed in various tissues, including the brain and placenta. Mutations or alterations in ABCB2 have been implicated in certain human diseases, though the exact mechanisms are not fully understood. Research continues to explore the function of ABCB2 in normal cellular processes and its potential involvement in disease pathogenesis. Its structure is characterized by two transmembrane domains and two nucleotide-binding domains, typical of ABC transporters.