2aminoaniline

2-Aminoaniline, also known as ortho-phenylenediamine (OPD), is an organic compound with the chemical formula C6H8N2. It is an aromatic amine, consisting of a benzene ring substituted with two amino groups at adjacent positions. It is a colorless to light brown crystalline solid that is soluble in water and organic solvents.

2-Aminoaniline is an important intermediate in the synthesis of various heterocyclic compounds, particularly benzimidazoles. These benzimidazole derivatives find applications in pharmaceuticals, agrochemicals, and dyes. For instance, it is used in the production of anthelmintics, fungicides, and corrosion inhibitors. The compound can also be used as a photographic developer and in the synthesis of certain polymers.

The synthesis of 2-aminoaniline typically involves the reduction of 2-nitroaniline. Various reducing agents can be employed for this purpose, including catalytic hydrogenation or the use of metals like iron or tin in acidic conditions.

Safety precautions should be taken when handling 2-aminoaniline as it can be irritating to the skin, eyes, and respiratory tract. It is also considered a sensitizer. Proper ventilation and personal protective equipment are recommended.