236Trimethylpyridine

2,3,6-Trimethylpyridine, also known as 2,3,6-collidine, is a heterocyclic organic compound with the chemical formula C8H11N. It is a derivative of pyridine, a six-membered ring containing one nitrogen atom, with three methyl groups attached at the 2, 3, and 6 positions.

This compound typically appears as a colorless to pale yellow liquid with a characteristic pyridine-like odor. Its physical properties include a boiling point of approximately 170-171 degrees Celsius and a melting point around -35 degrees Celsius. 2,3,6-Trimethylpyridine is soluble in many organic solvents and moderately soluble in water.

2,3,6-Trimethylpyridine is primarily used as a chemical intermediate in the synthesis of various organic compounds. It can serve as a building block for pharmaceuticals, agrochemicals, and specialty chemicals. Its reactivity stems from the nitrogen atom in the pyridine ring and the presence of the methyl substituents, which can influence its participation in reactions such as alkylation, acylation, and oxidation.

Due to its chemical nature, 2,3,6-trimethylpyridine should be handled with appropriate safety precautions. It is considered an irritant and may be harmful if inhaled, swallowed, or absorbed through the skin. Proper ventilation and personal protective equipment are recommended when working with this substance.