proteasomijakelun
Proteasome is a multicatalytic proteinase complex that plays a crucial role in the degradation of intracellular proteins. It is found in all eukaryotic cells and is essential for various cellular processes, including protein quality control, cell cycle regulation, and immune response. The proteasome is composed of a 20S core particle, which contains three types of subunits (alpha, beta, and gamma) arranged in a cylindrical structure, and a 19S regulatory particle, which caps the 20S core and facilitates substrate recognition and unfolding.
The 20S core particle is responsible for the proteolytic activity of the proteasome. It contains three active
The proteasome is involved in various cellular processes, including protein quality control, cell cycle regulation, and
The proteasome is a highly regulated enzyme, and its activity is tightly controlled by various factors, including