mmünomodülatörler

Immunomodulators are substances that can alter or modulate the immune system's activity. They can either stimulate (immunoaugmen tation) or suppress (immunosuppression) the immune response. This modulation can occur through various mechanisms, affecting different components of the immune system like T cells, B cells, cytokines, or innate immune cells.

The applications of immunomodulators are broad and significant in medicine. Immunosuppressive drugs are crucial in preventing organ transplant rejection and in treating autoimmune diseases where the immune system mistakenly attacks the body's own tissues. Examples include corticosteroids, calcineurin inhibitors, and mycophenolate mofetil.

Conversely, immunostimulatory agents are used to boost the immune system's ability to fight infections or cancer. Vaccines, for instance, are a form of immunotherapy that primes the immune system. Other immunostimulants are being investigated or used to enhance anti-cancer immunity, such as interferons or checkpoint inhibitors.

The development and use of immunomodulators require careful consideration of their specific targets, potential side effects, and the delicate balance of the immune system. Research continues to identify novel immunomodulatory pathways and develop more targeted and effective therapies.