kaspase7

Kaspase-7, also known as CASP-7, is a member of the caspase family of cysteine aspartate-specific proteases, which play a crucial role in programmed cell death, or apoptosis. Kaspase-7 is involved in the execution phase of apoptosis, where it directly cleaves and activates other caspases, such as Kaspase-3, leading to the degradation of cellular proteins and the ultimate demise of the cell. It is expressed in various tissues and is regulated by multiple factors, including pro-apoptotic and anti-apoptotic proteins. Kaspase-7 is also implicated in other cellular processes, such as inflammation and cell differentiation. Its dysregulation has been linked to various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. The study of Kaspase-7 and its role in apoptosis has provided valuable insights into the molecular mechanisms underlying cell death and has opened up new avenues for therapeutic interventions in disease states.