indol1yl

Indolyl refers to a chemical radical or substituent derived from indole. Indole itself is a heterocyclic aromatic organic compound with the chemical formula C8H7N. It consists of a bicyclic structure, comprising a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring. The "indolyl" designation specifically indicates that one or more hydrogen atoms have been removed from the indole molecule, allowing it to form a bond with another chemical species.

The indolyl group can be attached to other molecules at various positions on the indole ring. The most common indolyl substituents are derived from attachment at the 1-position (N-indolyl) or the 3-position (3-indolyl), though other positions are also possible. This versatility in attachment points contributes to the diverse range of compounds that contain the indolyl moiety.

Indolyl-containing compounds are prevalent in nature and play significant roles in biological systems. For instance, the amino acid tryptophan contains an indole ring, and its derivatives, such as serotonin and melatonin, are important neurotransmitters and hormones. Synthetic compounds incorporating the indolyl structure are also synthesized and utilized in pharmaceuticals and other chemical applications due to the indole core's chemical properties and biological activity.