fruktoosi16bisfosfaatti

Fruktoosi-1,6-bisfosfaatti, often abbreviated as F-1,6-BP, is a key intermediate molecule in glycolysis, the metabolic pathway that breaks down glucose to produce energy. It is a phosphorylated form of fructose, meaning it has two phosphate groups attached to it. Specifically, the phosphate groups are located at the 1 and 6 positions of the fructose molecule.

The formation of fructose-1,6-bisfosfaatti from fructose-6-phosphate is a crucial regulatory step in glycolysis. This reaction is catalyzed by the enzyme phosphofructokinase-1 (PFK-1), which is considered a major control point of the entire pathway. The presence of F-1,6-BP signals that the cell has sufficient glucose available and is committed to proceeding through glycolysis.

Once formed, fructose-1,6-bisfosfaatti is then cleaved into two three-carbon sugar phosphates: dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). These two molecules can interconvert, but glyceraldehyde-3-phosphate is the form that directly enters the subsequent steps of glycolysis to generate ATP, the cell's primary energy currency. F-1,6-BP plays a vital role in energy production and is central to carbohydrate metabolism in virtually all organisms.