doseadditivity
Dose additivity is a pharmacological concept describing how the effect of two or more agents with similar mechanisms can be predicted from their doses. In a dose-additive interaction, the combination behaves as if the agents were diluted relative to each other, such that the total effect at a given level can be obtained by summing doses on an equivalent potency scale.
A formal approach to dose additivity is Loewe additivity. For a fixed effect level, let D1 and
Applications of dose additivity include the assessment of drug combinations in therapy and the evaluation of