PDE3entsyymejä
PDE3entsyymejä refer to phosphodiesterase 3 enzymes. These enzymes are part of a larger family of phosphodiesterase enzymes that play a critical role in cellular signaling by hydrolyzing cyclic nucleotides, specifically cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). The PDE3 family is unique in its ability to hydrolyze both cAMP and cGMP, although it shows a higher affinity for cAMP.
There are two main isoforms of PDE3: PDE3A and PDE3B. PDE3A is primarily found in cardiac and
Inhibition of PDE3 enzymes has been explored for therapeutic purposes. For example, drugs that inhibit PDE3,