Lipoksiinit
Lipoksiinit are a group of lipid mediators derived from polyunsaturated fatty acids, primarily arachidonic acid. They play crucial roles in various biological processes, including inflammation, immune responses, and cell signaling. The synthesis of lipoksiinit involves the action of lipoxygenases, enzymes that introduce oxygen atoms into fatty acids. Different types of lipoxygenases exist, leading to the formation of various lipoksiinit structures. These compounds can exert their effects by binding to specific receptors on target cells. For example, certain lipoksiinit have been implicated in the pathogenesis of asthma and other inflammatory diseases. They can influence the recruitment and activation of immune cells, modulate vascular permeability, and contribute to tissue damage. Research into lipoksiinit continues to uncover their complex physiological functions and their involvement in both health and disease. Understanding the pathways of lipoksiinit formation and their downstream effects is important for developing targeted therapeutic strategies.