FrozenSectionUntersuchung

Frozen Section is a term used in pathology to describe a thin slice of tissue that has been rapidly frozen and sectioned at a very low temperature. This technique is commonly used in diagnostic pathology to preserve the morphology of cells and tissues, allowing for detailed examination under a microscope. The process involves rapidly freezing the tissue to prevent ice crystal formation, which can distort cellular structures. The tissue is then sectioned using a cryostat, a specialized machine that cuts the frozen tissue into thin slices. These slices are typically 5-10 micrometers thick and are mounted onto a glass slide for staining and microscopic examination. Frozen Section is particularly useful for diagnosing certain conditions, such as infections, inflammatory diseases, and tumors, where rapid diagnosis is crucial. It provides a more accurate representation of the tissue's original structure compared to conventional histological techniques, which involve fixing and embedding the tissue before sectioning. The technique is widely used in clinical settings, research laboratories, and forensic pathology departments.